Congenital Adrenal Hyperplasia (CAH) Pediatric Profile One−21-Hydroxylase Deficiency Screen (Endocrine Sciences)

Casandra

Casandra Test Code LC44636Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 501568CPT Codes 82157, 82533, 82626, 83498, 84403

Congenital Adrenal Hyperplasia (CAH) Pediatric Profile One−21-Hydroxylase Deficiency Screen (Endocrine Sciences)

Clinical Use

Use

The Congenital Adrenal Hyperplasia (CAH) Pediatric Profile One−21-Hydroxylase Deficiency Screen is used to evaluate pediatric patients for the presence of congenital adrenal hyperplasia due to 21-hydroxylase deficiency. This disorder impacts the adrenal glands' capability to produce cortisol and aldosterone, leading to excess androgen production. Early diagnosis and management can prevent severe complications such as electrolyte imbalance, dehydration, and potentially life-threatening adrenal crisis.

Special Instructions

Serum must be separated from cells within 45 minutes of venipuncture. To avoid delays in turnaround time, submit separate frozen specimens if multiple tests are requested. Store blood samples in red-top tubes; do not use gel-barrier tubes.

Limitations

This test may not detect all forms of adrenal hyperplasia, as it primarily focuses on 21-hydroxylase deficiency. Results should be considered in conjunction with clinical evaluation and not be used as the sole basis for treatment decisions. Variables such as recent illness or physiological stress may affect hormone levels and potentially alter test outcomes. Interpretation of results requires consideration of patient age, gender, and clinical status.

Test Details