Endomysial Antibody, IgA
Use
Tissue transglutaminase is the autoantigen recognized by endomysial antibody in celiac disease.1
Special Instructions
This test requires a serum specimen collected in a red-top tube or gel-barrier tube. Ensure that hemolysis, lipemia, and microbial contamination are avoided, as these are causes for rejection.
Limitations
The test is designed to detect IgA class antibodies. It's important to note that in patients with IgA deficiency, which is more common in individuals with celiac disease, this test may yield false-negative results. In such cases, alternative testing strategies, like testing for anti-tissue transglutaminase (tTG) IgG antibodies, might be necessary. Additionally, test results should be used in conjunction with other diagnostic information, including histology and clinical findings.
Methodology
Immunoassay (IFA)
Biomarkers
LOINC Codes
- 10362-2
- 10362-2
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Storage Instructions
Refrigerate
Causes for Rejection
Lipemia; hemolysis; microbially-contaminated sera
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |