Endomysial Antibody, IgG

Casandra

Casandra Test Code AR66274Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2005501CPT Code 86231

Endomysial Antibody, IgG

Also known as: EMA IGG

Clinical Use

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Use

The presence of endomysial antibodies IgG, may be useful in identifying IgA-deficient patients at risk for celiac disease. Positive results from this test must be confirmed through a biopsy of the small intestine to establish a diagnosis of celiac disease. It is noteworthy that IgA deficiency can affect the interpretation of other serological tests, thereby making IgG-based tests valuable in such contexts. As a result, this test aids in identifying individuals who may benefit from further diagnostic evaluation.

Special Instructions

The test is not recommended as an initial evaluation for suspected celiac disease. The preferred approach for screening suspected cases of celiac disease is the Celiac Disease Reflexive Cascade, Serum (3016817). It is important for healthcare providers to consider the broader clinical context, such as symptoms and risk factors alongside the test results, and follow up with further testing like a small intestine biopsy if the results are positive.

Limitations

This test was developed and performed in a CLIA-certified laboratory, and has been established for clinical purposes. However, the test has not been cleared or approved by the US Food and Drug Administration (FDA). Furthermore, while positive results may suggest celiac disease in IgA-deficient patients, definitive diagnosis requires further confirmation via a biopsy of the small intestine. Therefore, interpretation should be contextualized within comprehensive clinical findings.

Test Details

New York Approved