Factor II (Prothrombin), DNA Analysis
Also known as: Prothrombin DNA, Prothrombin Gene Analysis, Prothrombin Gene Mutation
Use
Contributes to the risk assessment for venous thromboembolis thromboembolism (VTE) to better inform decisions regarding treatment and clinical management decisions of patients with relevant personal history of VTE and potential preventative care for patients with significant family history of VTE.
Special Instructions
Not provided.
Limitations
The variant analyzed is c.*97G>A, previously referred to as G20210A. Results must be combined with clinical information for accurate interpretation. Molecular-based testing is highly accurate, but diagnostic errors may occur due to factors such as genetic variants, blood transfusions, bone marrow transplantation, somatic or tissue-specific mosaicism, mislabeled samples, or erroneous representation of family relationships. This test has not been cleared or approved by the FDA.
Methodology
PCR-based (PCR)
Biomarkers
F2
Gene
LOINC Codes
- 24476-4 - F2 gene Mut Anl Bld/T
- 24475-6 - F2 c.20210G>A Geno Bld/T
- 56850-1 - Imp & review of lab results
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
7 mL
Minimum Volume
3 mL
Container
Lavender-top (EDTA) tube, yellow-top (ACD) tube
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Frozen specimen; hemolysis; quantity not sufficient for analysis; improper container
Other tests from different labs that may be relevant