Fentanyl and Norfentanyl, Serum or Plasma
Use
Relief of pain adjunct to general or regional anesthesia moderate to moderately-severe pain. Indications for monitoring include the following: to confirm or identify suspected drug toxicity in chronic use, therapeutic misadventure, or accidental or intentional acute overdose; to aid in the identification of an unknown drug ingested in unknown quantities, drug identification and/or quantitation may be performed as an adjunct for patient management; to monitor selected patient groups at greater risk for analgesic drug toxicity or drug-to-drug interaction; to confirm complete drug absorption and adequate drug elimination as an adjunct to overdose management.
Special Instructions
Not provided.
Limitations
This test was developed and its performance characteristics determined by Labcorp. However, it has not been cleared or approved by the Food and Drug Administration (FDA), which may impact its regulatory acceptance in certain clinical settings. Additionally, gel-barrier tubes are not recommended for specimen collection as they may affect the accuracy of the test results. The test is sensitive to certain serum/plasma collection methods and might require confirmatory or additional reflex tests in some cases.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 11074-2
- 3636-8
- 3636-8
- 11074-2
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
1 mL
Container
Red-top (no additive) tube or green-top (heparin) tube; gel-barrier tubes are not recommended
Collection Instructions
Transfer separated serum or plasma to a plastic transport tube. Collection time: trough.
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
