Free κ and λ Light Chains Plus Ratio, Quantitative

Also known as: Freelite®, Kappa Free Light Chains, Quantitative, Serum, Kappa:Lambda Free Light Chains Ratio, Quantitative, Serum, Kappa:Lambda Free Light Chains, Quantitative, Serum, Lambda Free Light Chains, Quantitative, Serum

Clinical Use

Order Test

Use

Free light chain (FLC) results should be considered under the following categories and investigated appropriately (κ = kappa free light chain; λ = lambda free light chain).

Special Instructions

Not provided.

Limitations

This test is not intended for interchangeability with other assay methods in serial testing. It should be used consistently with one method to monitor a patient’s course of therapy. Furthermore, sample integrity is vital; microbially contaminated, particulate, lipemic, or hemolyzed specimens will be rejected. The test is intended as a one-time diagnostic tool rather than for ongoing monitoring.

Test Details

Methodology

Automated Analyzer (Clinical Chemistry)

Biomarkers

Free κ light chains

Analyte

κ free light chain quantitation

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Free λ light chains

Analyte

λ free light chain quantitation

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

κ:λ light chain ratio

Analyte

κ:λ light chain ratio

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

57778-3 - Immunoglobulin LC free Pnl Ser

Result Codes

36916-5 - Kappa LC Free Ser-mCnc
33944-0 - Lambda LC Free SerPl-mCnc
48378-4 - Kappa LC Free/Lambda Free Ser

Result Turnaround Time

1-3 days

Specimen

Serum

Volume

0.5 mL

Minimum Volume

0.2 mL

Container

Red-top tube or gel-barrier tube

Collection Instructions

Sample should be allowed to clot and the serum separated as soon as possible to prevent hemolysis. For requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.