Free κ and λ Light Chains Plus Ratio, Quantitative
Also known as: Freelite®, Kappa Free Light Chains, Quantitative, Serum, Kappa:Lambda Free Light Chains Ratio, Quantitative, Serum, Kappa:Lambda Free Light Chains, Quantitative, Serum, Lambda Free Light Chains, Quantitative, Serum
Use
Free light chain (FLC) results should be considered under the following categories and investigated appropriately (κ = kappa free light chain; λ = lambda free light chain).
Special Instructions
Not provided.
Limitations
This test is not intended for interchangeability with other assay methods in serial testing. It should be used consistently with one method to monitor a patient’s course of therapy. Furthermore, sample integrity is vital; microbially contaminated, particulate, lipemic, or hemolyzed specimens will be rejected. The test is intended as a one-time diagnostic tool rather than for ongoing monitoring.
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
Free κ light chains
AnalyteFree λ light chains
Analyteκ:λ light chain ratio
Analyte
LOINC Codes
- 57778-3 - Immunoglobulin LC free Pnl Ser
- 36916-5 - Kappa LC Free Ser-mCnc
- 33944-0 - Lambda LC Free SerPl-mCnc
- 48378-4 - Kappa LC Free/Lambda Free Ser
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Sample should be allowed to clot and the serum separated as soon as possible to prevent hemolysis. For requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Refrigerate; samples are stable for 21 days at 2°C to 8°C. For longer storage, freeze at -20°C.
Causes for Rejection
Microbially-contaminated specimen; specimen containing particulate matter; lipemic or hemolyzed specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 21 days |
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