GM1 IgM Autoantibodies
Use
The BUHLMANN™ Anti-GM1 IgM ELISA is intended for the qualitative determination of human IgM autoantibodies directed against monosialotetrahexosylganglioside (GM1) in human serum.1
Special Instructions
Not provided.
Limitations
Anti-GM1 IgM seropositivity supports but does not confirm MMN diagnosis. Seronegativity does not exclude it. IgM Anti-GM1 is also seen in other conditions such as Guillain-Barré syndrome, motor axonal neuropathy, and polyneuropathy. The test must be used with other clinical evaluations to confirm disease. It is not FDA-reviewed or approved.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 43241-9 - GM1 Gangl IgM Titr Ser IA
- 43241-9 - GM1 Gangl IgM Titr Ser IA
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.3 mL
Minimum Volume
0.1 mL
Container
Gel-barrier tube or red-top tube
Collection Instructions
Separate serum from cells. Transfer the serum into a Labcorp PP transpak frozen purple tube with screw cap. Freeze immediately and maintain frozen at ≤ -20°C until tested.
Patient Preparation
Lipemic samples can be avoided by having the patient fast for 12 hours prior to collection.
Storage Instructions
Freeze.
Causes for Rejection
Non-serum sample received; non-frozen serum received; grossly lipemic, hemolytic or icteric sample received
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 4 months |
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