Group B Streptococcus Colonization Detection, NAA With Reflex to Susceptibilities

Clinical Use

Use

Antepartum detection of group B β-hemolytic streptococci in patients who are at high risk for anaphylactic shock due to penicillin allergy.

Special Instructions

Not provided.

Limitations

A positive result does not necessarily indicate the presence of viable organisms. Patients who have used systemic or topical (vaginal) antibiotic treatment in the week prior or those diagnosed with placenta previa should not be tested using this assay. Susceptibility testing is generally not performed as GBS is universally susceptible to penicillin, though exceptions are made for penicillin-allergic patients at high risk for anaphylactic shock.

Test Details

Methodology

PCR-based (qPCR)

Biomarkers

Group B Streptococcus

Microorganism

Other

Other • Binary (Detected / Not Detected)

LOINC Codes

Order Codes

48683-7 - Gp B Strep DNA Spec Ql NAA+probe

Result Codes

48683-7 - Gp B Strep DNA Spec Ql NAA+probe

Result Turnaround Time

2-5 days

Specimen

Cervical Swab

Volume

Single or double bacterial swab in Amies agar gel transport, ESwab® or equivalent

Minimum Volume

Single bacterial swab in Amies agar gel transport, ESwab® or equivalent

Container

Bacterial Cult Trans Swab with Media or ESwab®

Collection Instructions

Swab the lower vagina (vaginal introitus), followed by the rectum using the same swab. Move swab from side to side, or rotate the swab at the collection site, allowing several seconds for absorption of organisms by the swab. Avoid using a speculum.

Storage Instructions

Specimen is stable for 24 hours at room temperature. If arrival at lab will extend beyond 24 hours, refrigerate.

Causes for Rejection

Inappropriate specimen transport; inappropriate transport conditions; improper labeling; specimen received after prolonged delay (more than 48 hours); cervical/endocervical, perianal, perirectal or perineal specimen or any source other than vagina and rectum