Hepatitis B Core Antibody, Total
Also known as: Anti-HBc, Antibody to Hepatitis B Core Antigen, Core Antibody, HBV
Use
This assay can be used as an aid in the diagnosis of individuals with acute or chronic hepatitis B virus (HBV) infection and in the determination of the clinical status of HBV infected individuals in conjunction with other HBV serological markers associated with HBV infection. This assay can also be used as an aid in the differential diagnosis in individuals displaying signs of hepatitis in whom etiology is unknown.
Special Instructions
Not provided.
Limitations
The results from this or any other diagnostic kit should be used and interpreted only in the context of the overall clinical picture. A negative test result does not exclude the possibility of exposure to hepatitis B virus. Levels of anti-HBc may be undetectable both in early infection and later after infection. This is a qualitative assay; reported antibody level cannot be correlated to an endpoint titer. Assay performance characteristics have not been established for immunocompromised or immunosuppressed patients.
Methodology
Immunoassay (CLIA)
Biomarkers
Hepatitis B Core Antibody IgM/IgG
Protein
LOINC Codes
- 13952-7 - HBV core Ab SerPl Ql IA
- 13952-7 - HBV core Ab SerPl Ql IA
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Gel-barrier tube, red-top tube or serum transfer tube
Collection Instructions
If tube other than a gel-barrier tube is used, transfer separated serum to a screw-cap polypropylene transport tube. Do not freeze gel-barrier tube (pour off serum first).
Storage Instructions
Room temperature
Causes for Rejection
Non-EDTA plasma specimen; PST gel-barrier tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant