Hepatitis D Virus (HDV) Antibody, IgG and IgM
Also known as: HBV, Hepatitis delta
Use
This assay is used for the qualitative detection of Hepatitis D virus (HDV) antibodies (IgG/IgM) and is intended to aid in the diagnosis of HDV infection in individuals with known HBV infection (HBsAg-positive). Testing for HDV RNA should be performed on HDV antibody-positive individuals to differentiate between active and resolved HDV infection.
Special Instructions
Not provided.
Limitations
A reactive specimen should be investigated further with sensitive, supplemental HDV-specific tests, such as identification of HDV RNA, to be matched with the clinical story of the subject and with markers of a previous HBV infection (HBsAg, anti-HB Core, HBV DNA, etc.). Like all immunoassays, this assay may occasionally yield nonspecific reactions due to other causes. A nonreactive test result for HDV antibodies does not exclude the possibility of exposure to or infection with HDV. Further investigations with alternative HDV-specific tests are suggested in case of suspected infection despite the negative finding.
Methodology
Immunoassay (CLIA)
Biomarkers
HDV Antibody, IgG/IgM
Analyte
LOINC Codes
- 40727-0 - HDV Ab Ser Ql IA
- 40727-0 - HDV Ab Ser Ql IA
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
Gel-barrier tube or lavender-top (EDTA) tube
Collection Instructions
Standard blood collection technique
Storage Instructions
Room temperature
Causes for Rejection
Gross hemolysis, lipemia or visible microbial contamination; heat-inactivated samples; specimens other than serum and EDTA plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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