Human Immunodeficiency Virus 1 (HIV-1) DNA Sequencing Protease−Reverse Transcriptase
Also known as: Cell-associated Viral DNA, HIV-1 Genotype, Resistance Analysis
Use
Detect resistance of HIV-1 to protease and reverse transcriptase inhibitors in cell-associated viral DNA.
Special Instructions
Not provided.
Limitations
This procedure should be used for patients with documented HIV-1 infection and undetectable viral load or low level viremia. Careful interpretation of results is necessary, as the presence of resistance-associated mutations depends on several factors, including sampling time relative to antiretroviral therapy and the overall viral load.
Methodology
NGS
Biomarkers
LOINC Codes
- 80692-7 - HIV1 proviral DNA RT + PR Mut Det Seq
- 80695-0 - HIV 1 proviral DNA Gentyp Bld MC Doc
- 80692-7 - HIV1 proviral DNA RT + PR Mut Det Seq
- 80694-3 - HIV1 proviral DNA Gentyp Bld MC Nar
Result Turnaround Time
10-14 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
4 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA) tube
Collection Instructions
Collect specimen in lavender-top (EDTA) tube. Do not centrifuge. Ship frozen.
Storage Instructions
Freeze.
Causes for Rejection
Quantity not sufficient for analysis; heparinized plasma; nonfrozen specimen
Other tests from different labs that may be relevant