Human Immunodeficiency Virus 1 (HIV-1) GenoSure® MG Genotyping
Also known as: HIV-1 Genotype, Resistance Analysis, Retroviral Genotype
Use
Detect resistance in HIV-1 to antiretroviral drugs targeted at the reverse transcriptase (nucleoside and nonnucleoside inhibitors) and protease.
Special Instructions
A separate frozen specimen is required for each frozen test ordered. Ensure immediate freezing of specimens and shipping them frozen to avoid delays and preserve sample integrity.
Limitations
This procedure may not be successful when the HIV viral load is less than 500 copies/mL of plasma, potentially leading to inconclusive results. If there is insufficient virus to produce results, HIV-1 RNA quantitation will be performed to confirm viral load, and the procedure will be billed at the account's prevailing fee. The test has not been cleared or approved by the FDA.
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 53798-5
- 49573-9
- 8251-1
- 53798-5
Result Turnaround Time
12-15 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
5 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA) or plasma preparation tube (PPT™)
Collection Instructions
Collect specimen in three lavender-top (EDTA) tubes or three PPT™ tubes. Do not use green-top (heparin) tubes. Centrifuge specimen within six hours of collection. Transfer plasma to one or more screw-cap polypropylene transport tube(s). Snap-cap or pop-top tubes should be avoided and may result in specimen rejection. Immediately freeze specimen at -20°C. Do not place samples on dry ice until completely frozen. Ship specimens frozen.
Storage Instructions
Freeze.
Causes for Rejection
PPT™ not centrifuged; insufficient volume; heparinized plasma; nonfrozen specimens; specimens exposed to repeated freeze/thaw cycles