Human Immunodeficiency Virus Type 1 (HIV-1) PhenoSense GT Plus Integrase
Also known as: HIVPS PLUS
Use
Intended for use in patients with viral loads ā„500 copies/mL. This test provides combined pheno- and genotyping results to offer antiretroviral susceptibility information for protease inhibitors, reverse transcriptase inhibitors, and integrase inhibitors. It is the preferred test for patients with known or suspected complex drug resistance patterns, such as suboptimal virologic response to treatment and viral load rebound.
Special Instructions
This procedure should be used for patients with documented HIV-1 infection and viral loads greater than 500 copies/mL.
Limitations
The test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered. Thawed specimens are unacceptable, and the stability of the specimens is restricted to being frozen for up to 2 weeks. The test cannot provide susceptibility information if the viral load is below 500 copies/mL.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 51969-4
- 83326-9
- 49665-3
- 19146-0
- 77202-0
Result Turnaround Time
27-38 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
5 mL
Minimum Volume
3 mL
Container
Lavender (EDTA) or plasma preparation tube (PPT).
Collection Instructions
Separate from cells within 6 hours of collection. Transfer plasma to ARUP standard transport tubes and freeze immediately.
Storage Instructions
CRITICAL FROZEN.
Causes for Rejection
Thawed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 2 weeks |
Other tests from different labs that may be relevant