Human Immunodeficiency Virus 1 (HIV-1) PhenoSense GT® Plus Integrase (Monogram® Phenotype + Genotype)
Also known as: HIV Resistance, PhenoSense GT® Plus Integrase
Use
Determines viral phenotype and genotype resistance to four classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors (NRTI), nonnucleoside reverse transcriptase inhibitors (NNRTI), protease inhibitors (PI), and integrase inhibitors (INI).
Special Instructions
Not provided.
Limitations
The procedure is intended for patients with documented HIV-1 infection and viral loads ≥500 copies/mL. Insufficient virus quantity may lead to alternative testing, with additional billing applied. Nonfrozen specimens, as well as those that experience repeated freeze/thaw cycles, will be rejected. PPT™ tubes must be centrifuged, and heparinized plasma will be discarded.
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 83326-9 - HIV 1 RNA geno + pheno Islt
- 51969-4 - Gene analysis narr rpt Doc
- 83326-9 - HIV 1 RNA geno + pheno Islt
- 49665-3 - HIV Susc Pnl Islt Phenotyp
- 80689-3 - HIV 1 RNA RT + PR + IN Mut Det Plas Seq
- 77202-0 - Laboratory comment Report
Result Turnaround Time
19-23 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
5 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA) tubes or PPT™ tubes
Collection Instructions
Centrifuge specimen within six hours of collection. Transfer plasma to one or more polypropylene screw-capped tube(s) and freeze. Ship specimen frozen.
Storage Instructions
Freeze.
Causes for Rejection
PPT™ not centrifuged; quantity not sufficient for analysis; heparinized plasma; nonfrozen specimens; specimens exposed to repeated freeze/thaw cycles; specimen received in 'pop-top' or 'snap-cap' tube
Other tests from different labs that may be relevant