Human Immunodeficiency Virus 1 (HIV-1) PhenoSense GT® (Monogram® Phenotype/Genotype)
Also known as: HIV-1 Resistance, PhenoSense GT®
Use
Determines viral phenotype and genotype resistance to three classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors (NRTI), nonnucleoside reverse transcriptase inhibitors (NNRTI), and protease inhibitors (PI). Viral replication capacity is also included.
Special Instructions
Not provided.
Limitations
The test should only be used for patients with documented HIV-1 infection and viral loads equal to or above 500 copies/mL. It has not been cleared or approved by the FDA, and results should not be used as the sole criteria for patient management.
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 51969-4 - Gene analysis narr rpt Doc
- 19146-0 - Ref Lab Test Results
- 49665-3 - HIV Susc Pnl Islt Phenotyp
- 53798-5 - HIV RT+PR Mut Det Islt
- 77202-0 - Laboratory comment Report
- 62364-5 - Test performance info Spec
Result Turnaround Time
16-22 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
3 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA) or plasma preparation tube (PPT™)
Collection Instructions
Collect specimen in two lavender-top (EDTA) tubes or two PPT™ tubes. Do not use green-top (heparin) tubes. Centrifuge specimen within six hours of collection. Transfer plasma to one or more polypropylene screw-capped tube(s) (not "pop-top" or "snap-cap"), and freeze. Ship specimen frozen.
Storage Instructions
Freeze
Causes for Rejection
PPT™ not centrifuged; quantity not sufficient for analysis; heparinized plasma; nonfrozen specimen; specimen exposed to repeated freeze/thaw cycles; specimen received in "pop-top" or "snap-cap" tube
Other tests from different labs that may be relevant