Human Immunodeficiency Virus 1 (HIV-1) PhenoSense GT® (Monogram® Phenotype/Genotype)
Also known as: HIV-1 Resistance, PhenoSense GT®
Use
Determines viral phenotype and genotype resistance to three classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors (NRTI), nonnucleoside reverse transcriptase inhibitors (NNRTI), and protease inhibitors (PI). Viral replication capacity is also included.
Special Instructions
A separate frozen specimen is required for each frozen test ordered. This assay is a combined assay in which HIV genotype and HIV phenotype is performed.
Limitations
The test should only be used for patients with documented HIV-1 infection and viral loads equal to or above 500 copies/mL. It has not been cleared or approved by the FDA, and results should not be used as the sole criteria for patient management.
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 51969-4
- 19146-0
- 49665-3
- 53798-5
- 77202-0
- 62364-5
Result Turnaround Time
16-22 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
3 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA) or plasma preparation tube (PPT™)
Collection Instructions
Collect specimen in two lavender-top (EDTA) tubes or two PPT™ tubes. Do not use green-top (heparin) tubes. Centrifuge specimen within six hours of collection. Transfer plasma to one or more polypropylene screw-capped tube(s) (not "pop-top" or "snap-cap"), and freeze. Ship specimen frozen.
Storage Instructions
Freeze
Causes for Rejection
PPT™ not centrifuged; quantity not sufficient for analysis; heparinized plasma; nonfrozen specimen; specimen exposed to repeated freeze/thaw cycles; specimen received in "pop-top" or "snap-cap" tube
Other tests from different labs that may be relevant