Human Immunodeficiency Virus 1 (HIV-1) GenoSure PRIme®

Casandra

Casandra Test Code LC22500Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 551700

Human Immunodeficiency Virus 1 (HIV-1) GenoSure PRIme®

Also known as: GenoSure PRime®, HIV-1 Genotype, POL Genotype, Resistance Testing, Retroviral Genotype

Clinical Use

Order Test

Use

Detect resistance of HIV-1 to protease, reverse transcriptase, and integrase inhibitors.

Special Instructions

Submit a separate frozen specimen for each test requested to avoid delays in turnaround time. The specimen must be collected in designated lavender-top (EDTA) tubes or plasma preparation tubes (PPT™), centrifuged within six hours of collection, and then stored and shipped frozen. Snap-cap or pop-top tubes should be avoided, as they may lead to specimen rejection.

Limitations

This procedure may not be successful when the HIV viral load is below 500 copies/mL plasma. In cases where insufficient virus is present, HIV-1 RNA quantitation will be performed to confirm viral load. The test has high reproducibility and sensitivity, but results may be limited by the inability to determine subtype info confidently if not enough data is available.

Test Details

Methodology

PCR-based (PCR)

Biomarkers

4 targets

IntegraseNo genesProteaseReverse Transcriptase

LOINC Codes

Order Codes

80689-3

Result Codes

51969-4
8251-1
80689-3
62364-5

Result Turnaround Time

11-14 days

Specimen

Plasma

Volume

5 mL

Minimum Volume

Not provided

Container

Lavender-top (EDTA) or plasma preparation tubes (PPT™)

Collection Instructions

Collect specimen in three lavender-top (EDTA) tubes or three PPT™ tubes. Centrifuge specimen within six hours of collection. Transfer plasma to one or more screw-cap polypropylene transport tube(s). Do not use snap-cap or pop-top tubes.