Human Immunodeficiency Virus 1 (HIV-1) Trofile® Select
Also known as: Coreceptor Tropism (Phenotypic), HIV Coreceptor Tropism Phenotype, Tropism
Use
Trofile® Select allows for the determination of HIV-1 coreceptor tropism status, by which the appropriate assay, Trofile® or Trofile® DNA, is selected through an initial prescreening viral assessment. The coreceptor tropism status may be used to determine eligibility for CCR5 antagonist therapy, such as maraviroc (Selzentry®).
Special Instructions
Not provided.
Limitations
This procedure should be used only for patients with documented HIV-1 infection.
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 51969-4 - Gene analysis narr rpt Doc
- 50790-5 - HIV1 RNA tropism Islt
- 57182-8 - HIV1 RNA tropism Plas
- 77202-0 - Laboratory comment Report
- 49549-9 - Ref lab test method
- 75608-0 - Citation Ref Lab Test
- 80690-1 - HIV1 proviral DNA tropism Bld MC
- 62364-5 - Test performance info Spec
Result Turnaround Time
33-41 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
5 mL
Minimum Volume
Not provided
Container
Lavender-top (EDTA)
Collection Instructions
Centrifuge three tubes within six hours of collection. Remove plasma, transfer plasma to screw-cap polypropylene transport tubes, and freeze. Ship specimen frozen.
Storage Instructions
Freeze.
Causes for Rejection
Both frozen plasma and frozen whole blood not received; insufficient volume; heparinized plasma; specimen not frozen
Other tests from different labs that may be relevant