Lactoferrin, Fecal, Quantitative

Also known as: Fecal Lactoferrin, Fecal Leukocytes, IBD-Scan®, Stool Lactoferrin

Clinical Use

Use

An in vitro diagnostic aid to distinguish patients with active inflammatory bowel disease (IBD) from those with inactive IBD, as well as from noninflammatory irritable bowel syndrome (IBS).

Special Instructions

Not provided.

Limitations

The test may not be appropriate for immunocompromised individuals, patients with a history of HIV, hepatitis B and C, infectious diarrhea within the past six months, or those who have had a colostomy or ileostomy within the last month. Fecal lactoferrin levels should be interpreted in conjunction with a full patient evaluation since other intestinal ailments, including gastrointestinal infections and colorectal cancer, may also raise lactoferrin levels.

Test Details

Methodology

Immunoassay (ELISA)

Biomarkers

Lactoferrin

Analyte

Lactoferrin Quantitation

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

42924-1 - Lactoferrin Stl-mCnc

Result Codes

42924-1 - Lactoferrin Stl-mCnc

Result Turnaround Time

4-8 days

Specimen

Stool

Volume

1 g

Minimum Volume

0.5 g

Container

Clean, screw-capped, plastic vial with no preservatives

Collection Instructions

Do not contaminate outside of container; do not overfill container. Loose/watery stools are acceptable. Ensure that no toilet tissue/sanitary materials are present in the submitted specimen. Ship refrigerated at 2°C to 8°C.

Storage Instructions

Refrigerate.

Causes for Rejection

Nonfecal sample received (eg, serum, plasma, urine); stool contaminated with urine; preserved stool received (eg, 10% formalin, sodium acetate formalin, or polyvinyl alcohol)