Occult Blood, Fecal by Immunoassay

Casandra

Casandra Test Code AR01397Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2007190CPT Code 82274

Occult Blood, Fecal by Immunoassay

Also known as: FOB IA

Clinical Use

Order Test

Use

The Occult Blood, Fecal by Immunoassay test is a qualitative assessment used primarily for the detection of lower gastrointestinal bleeding, which can be an indicator of colorectal cancer. The test is an immunoassay that detects fecal occult blood, specifically focusing on identifying bleeding from the lower regions of the gastrointestinal tract, thus aiding in the screening for colorectal cancer. A recommended cutoff of 100 ng/mL is used to provide a specificity of approximately 95 percent for colorectal cancer detection.

Special Instructions

The test requires stool samples which can be collected by patients in a home setting using a Patient Take Home Kit or in a clinical setting with a FOBT-CHEKoc sampling bottle. The stool must be transferred to the sampling bottle within 4 hours of collection to ensure sample integrity. Proper use of the ARUP supply kits and adherence to collection instructions is crucial for accurate results.

Limitations

This test does not detect upper gastrointestinal bleeding and no single cutoff is universally superior for colorectal cancer detection. Therefore, results should be interpreted in the context of the patient's overall clinical condition and history. The specificity of this assay is approximately 95 percent when using the manufacturer's recommended cutoff. External factors or improper sample handling may affect test results.

Test Details

New York Approved

Methodology

Immunoassay (Qualitative)

Biomarkers

Occult Blood

Analyte

Other • Binary (Detected / Not Detected)

LOINC Codes

Result Codes

2335-8

Result Turnaround Time

2-3 days

Specimen

Stool

Volume

Not provided

Minimum Volume

Not provided

Container

FOBT-CHEKoc sampling bottle (ARUP Supply #49940/#49952)

Collection Instructions

For Clinical Collections: Dip sampling bottle transfer wand into stool collection and place back into the sampling bottle. For Patient In-Home Collection: Use the Patient Take Home Kit for stool collection and transfer within 4 hours.