Maternal Cell Contamination
Use
This test is used to rule out the presence of maternal cell contamination within a fetal specimen to aid in the accurate interpretation of prenatal molecular genetic or cytogenetic results.
Special Instructions
Maternal samples sent for maternal cell contamination studies should be submitted under a separate requisition from fetal specimens (CVS or amniotic fluid).
Limitations
False positive or negative results may occur for reasons that include genetic variants, blood transfusions, bone marrow transplantation, or erroneous characterization of family relationships. Molecular-based testing is highly accurate, but as in any laboratory test, rare diagnostic errors may occur. Results are provided for identification of maternal cell contamination in the specimen itself, and not for diagnostic purposes.
Methodology
PCR-based (Multiplex)
Biomarkers
LOINC Codes
- 59266-7
- 31208-2
- 41103-3
- 72486-4
- 11502-2
Result Turnaround Time
11-21 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
8.5 mL
Minimum Volume
3 mL
Container
Lavender-top (EDTA) tube, pink-top (EDTA) tube, tan-top (EDTA) tube, yellow-top (ACD-A) tube
Collection Instructions
Standard phlebotomy
Storage Instructions
Whole blood: Room temperature stability 14 days, refrigerated 30 days at 4°C
Causes for Rejection
Frozen or hemolyzed specimen; quantity not sufficient for analysis; improper container
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 30 days |