Meperidine, Serum or Plasma
Also known as: Demerol®
Use
For therapeutic monitoring only (not for forensic purposes). Meperidine, a phenylpiperidine derivative, is a synthetic opioid analgesic. Many of its pharmacologic properties and indications are similar to those of morphine, but meperidine has no effect on cough and is much less constipating. It is 1/8 as potent as morphine on a weight basis when administered parenterally. Meperidine is about 1/3 to 1/4 as potent orally as parenterally.
Special Instructions
Collect specimen immediately prior to the next dose unless specified otherwise. Transfer separated serum or plasma to a plastic transport tube. Ensure correct collection to avoid rejection due to the use of gel-barrier tubes.
Limitations
The test is not cleared or approved by the FDA. Its performance characteristics were determined by Labcorp, and it is not suitable for forensic purposes. Testing may be affected by absorption variability among individuals, which can impact analgesic efficacy.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 3745-7
- 3745-7
Result Turnaround Time
3-4 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube.
Collection Instructions
Transfer separated serum or plasma to a plastic transport tube. Collect specimen immediately prior to next dose unless specified otherwise.
Storage Instructions
Room temperature
Causes for Rejection
Gel-barrier tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |