MYCN Oncology FISH
Also known as: FISH, Leukemia FISH, Lymphoma FISH
Use
Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability)
Special Instructions
Include pertinent clinical diagnosis and previous cytogenetic studies on the test request form. Utilize sterile technique and Labcorp transport kits when possible for specimen collection and transport to the testing laboratory at room temperature. Do not allow samples to overheat or freeze.
Limitations
Molecular mutations or chromosomal alterations not targeted by the probe included in this profile will not be detected. This test is developed and its performance characteristics are determined by Labcorp. It has not been cleared or approved by the FDA. Results should be interpreted within the context of histology, IHC, and a pathological evaluation. All paraffin-embedded tissues referred for FISH testing are reviewed by a pathologist.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- 31208-2
- 62361-1
- 62360-3
- 48674-6
- 50398-7
- 48672-0
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube (suboptimal). Adjust tube size to sample volume to avoid heparin toxicity.
Collection Instructions
Utilize sterile technique and Labcorp transport kits when possible.
Storage Instructions
Transport to the testing laboratory at room temperature; use of a cool pack or a Labcorp transport kit is acceptable. Do not allow samples to overheat or freeze.
Causes for Rejection
Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen