Casandra
Casandra Test Code LC16125Version 1 (DRAFT)
Performing Lab
Lab LabcorpLab Test ID 452357
pan‑TRK IHC
Also known as: NTRK
Clinical Use
Order TestUse
The pan-TRK IHC assay may be used to identify C-terminal protein expression of TRK A, B and C proteins as a surrogate marker of NTRK fusions in solid tumors. Depending on the histologic findings, a positive pan-TRK IHC test may need to be confirmed with an alternative test for NTRK fusions.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Immunoassay (IHC)
Biomarkers
TRK A
ProteinIHC
Expression • Ordinal Score (e.g., TPS, CPS, H-score)
TRK B
ProteinIHC
Expression • Ordinal Score (e.g., TPS, CPS, H-score)
TRK C
ProteinIHC
Expression • Ordinal Score (e.g., TPS, CPS, H-score)
LOINC Codes
Order Codes
- 452357
Result Codes
- 55229‑9
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tissue (FFPE)
Volume
Paraffin block or unstained positive charged slides
Minimum Volume
Three unstained slides
Container
Paraffin block or unstained positive charged slides
Collection Instructions
Three unstained positively charged slides with sections cut at 3‑6 microns or paraffin block
Storage Instructions
Room temperature
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