Porphobilinogen (PBG), Quantitative, Random Urine
Also known as: PBG Random Urine, Quantitative
Use
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms. Detect porphyrias and porphyrinurias. Acute intermittent porphyria is characterized by excretion of porphobilinogen and delta aminolevulinic acid in urine during acute attacks, but not during latency. Increased urine values are seen in the intoxication porphyrias (heavy metals, halogenated solvents, certain drugs).
Special Instructions
For 24-hour urine testing, order Porphobilinogen (PBG), Quantitative, 24-Hour Urine [003103].
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration, which may limit its application in certain regulatory environments.
Methodology
Other
Biomarkers
LOINC Codes
- 24446-7
- 24446-7
- 2161-8
- 13797-6
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
3 mL
Minimum Volume
1 mL
Container
Plastic urine container with 0.5 mL of 30% glacial acetic acid (optional preservative) and amber plastic frozen transport tube and cap (Labcorp No. 78656).
Collection Instructions
On collection of random urine, it is advisable not to use first voided morning specimen, late evening specimen after 8 PM, or specimen obtained following excessive fluid intake. Transfer the urine into a Labcorp amber plastic frozen transport tube with amber cap (Labcorp No. 78656). If ordered with Δ-ALA, pH must be <6. Label the container with the patient's name and date. The specimen should be frozen immediately and maintained frozen until tested. If amber tube and cap are not available, cover a clear plastic transport tube completely from top to bottom with aluminum foil. Identify the specimen with the patient's name directly on the transport tube and the outside of the aluminum foil. Secure with tape.
Storage Instructions
Freeze immediately and protect from light. Urine is stable when preserved with 30% glacial acetic acid and frozen for one month or refrigerated for 24 hours.
Causes for Rejection
Specimen exposed to light; specimen not received frozen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 24 hours |
| Frozen | 1 month |