Use

CMV: Routine screening of pregnant people for CMV is not recommended by current guidelines. Maternal CMV IgM antibody has limited clinical utility in differentiating primary from recurrent infection. An IgG-positive, IgM-negative result typically indicates past infection; however, IgG avidity testing, to determine the time since primary infection, should be considered if clinically warranted. An IgG-positive, IgM-positive result suggests recent primary infection and IgG avidity testing is recommended to determine the time since primary infection. An IgG-negative, IgM-positive result suggests very recent infection and the patient should be followed to document seroconversion. An IgG-negative, IgM-negative result indicates susceptibility to infection.