PrEP, Male, Oral Baseline + HIV RNA
Also known as: HIV, PrEP, Prophylaxis
Use
This profile aligns with current guidelines for assessment of male patients prior to the initiation of oral HIV PrEP.
Special Instructions
The profile requires a dedicated, unopened, gel-barrier tube and 2 frozen (preferred) or refrigerated serum pour-off tubes. Patients must be asked about biotin supplementation as it can interfere with the tests. It is recommended to stop biotin consumption 72 hours prior to sample collection.
Limitations
Results of HIV p24 antigen/antibody testing must be confirmed by additional tests if reactive. Negative results do not rule out HIV-1 and/or HIV-2 infection due to potential low marker quantity or absence during disease stages. GFR estimates based on serum creatinine may be inaccurate for patients at muscle mass extremes, with unusual diets, or conditions affecting creatinine secretion or elimination.
Methodology
PCR-based (RT-PCR)
Biomarkers
LOINC Codes
- 56888-1
- 25835-0
- 69353-1
- 55752-0
- 47236-5
- 43304-5
- 43305-2
- 5196-1
- 22322-2
- 13952-7
- 77202-0
- 56850-1
- 13955-0
- 2160-0
- 98979-8
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
12 mL
Minimum Volume
7 mL
Container
Gel-barrier tube
Collection Instructions
Serum specimen: Usual blood collection technique.
Patient Preparation
Patient should not have urinated for one hour prior to specimen collection.
Storage Instructions
Serum: Gel-barrier tubes refrigerated up to 6 days
Causes for Rejection
Hemolysis; lipemia; received outside of specimen and/or storage and/or labeling requirements; aliquot received for HIV testing; specimen in expired transport or incorrect transport device.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 30 days |
| Refrigerated | 6 days |
| Frozen | 6 weeks |