Recurrent Miscarriage/Fetal Demise Profile (Esoterix)
Also known as: Obstetric Complications Profile
Use
This profile is intended to evaluate a range of coagulation, thrombophilia, autoimmune, and genetic risk factors associated with recurrent miscarriage or fetal demise, including clotting factor mutations, lupus anticoagulant, antiphospholipid antibodies, homocysteine levels, and natural anticoagulant activities. It supports clinical investigation in women with obstetric complications or history of fetal loss.
Special Instructions
Not provided.
Limitations
This procedure may be considered by Medicare and other payers as investigational and, therefore, may not be payable as a covered benefit for patients.
Methodology
Other
Biomarkers
Result Turnaround Time
5-9 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Five 1‑mL tubes of platelet‑poor frozen citrated plasma
Minimum Volume
Not provided
Container
Blue‑top (sodium citrate) tube citrated platelet‑free plasma
Collection Instructions
Plasma/serum must be separated from cells within 45 minutes of venipuncture and plasma centrifuged a second time before being placed in plastic transport tubes. Freeze within two hours and keep frozen until testing is performed.
Storage Instructions
Freeze plasma or serum.
Causes for Rejection
Noncitrated plasma; gross hemolysis; presence of fibrin; clotted plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
Other tests from different labs that may be relevant