Streptococcus pneumoniae Antigen, Urine or Cerebrospinal Fluid
Also known as: BinaxNow® Streptococcus Antigen
Use
Detects S pneumoniae in the urine of patients with S pneumoniae and in the CSF of patients with meningitidis.
Special Instructions
A body fluid culture will be performed if not initially requested for S. pneumoniae for antigen-negative CSF specimens as per the College of American Pathologists (CAP) guidelines. This ensures comprehensive analysis and verification of results, supporting the initial antigen detection findings.
Limitations
Testing for Streptococcus pneumoniae antigens is not recommended for individuals who have received the Streptococcus pneumoniae vaccine within five days prior to testing, due to the potential for false-positive reactions. Additionally, the accuracy of this test in urine specimens has not been validated in young children, which may limit its applicability in pediatric populations where alternative diagnostic methods might be required. Consideration should be given to confirmatory tests to ensure diagnosis accuracy, especially in cases of suspected false-positive results.
Methodology
Immunoassay (Lateral Flow)
Biomarkers
LOINC Codes
- 31969-9
- 31208-2
- 31969-9
- 45335-7
- 636-1
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
1 mL
Minimum Volume
0.5 mL
Container
Plastic urine culture container
Collection Instructions
Clean-catch urine specimen per instructional protocol
Storage Instructions
Refrigerate. If specimen is not tested within seven days, freeze at -20ºC or below.
Causes for Rejection
Quantity not sufficient for analysis; inappropriate specimen source; inappropriate specimen collection device; specimen stability exceeded; name discrepancy between the name on the specimen container and the name in the computer or on the test request form