Thyroid-stimulating Hormone (TSH) in Pregnancy
Also known as: Thyrotropin in Pregnancy
Use
Assessment of thyroid function during pregnancy
Special Instructions
Biotin supplementation by the patient can interfere with test results; thus, it is essential to inquire about such supplements. Patients should stop biotin intake at least 72 hours before sample collection. TSH values can vary significantly depending on ethnicity, with African American and Asian women generally showing lower values than Caucasian women.
Limitations
Test readings can be affected by supplements containing high doses of biotin, which may result in incorrect interpretations. The assay sensitivity is 0.004 uIU/mL and is considered a third-generation TSH assay. It is important to understand ethnic and pregnancy-related variations in TSH levels when interpreting results.
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 11580-8
- 11580-8
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.7 mL
Container
Red-top tube, gel-barrier tube, or green-top (lithium heparin) tube
Collection Instructions
If a red-top tube or plasma is used, transfer separated serum or plasma to a plastic transport tube.
Patient Preparation
Stop biotin supplementation at least 72 hours before sample collection.
Storage Instructions
Room temperature. Stable at room temperature, refrigerated, or frozen for 14 days. Freeze/thaw cycles: stable x3
Causes for Rejection
Citrate plasma specimen; improper labeling
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |