Tramadol and O-Desmethyltramadol, Serum or Plasma
Use
Relief of moderate to moderately-severe pain. Indications for monitoring include the following: to confirm or identify suspected drug toxicity in chronic use, therapeutic misadventure, or accidental or intentional acute overdose; to aid in the identification of an unknown drug ingested in unknown quantities, drug identification and/or quantitation may be performed as an adjunct for patient management; to monitor selected patient groups at greater risk for analgesic drug toxicity or drug-to-drug interaction; to confirm complete drug absorption and adequate drug elimination as an adjunct to overdose management.
Special Instructions
For accurate results, it is preferable to measure trough levels, which are the lowest concentrations reached before the next dose of medication is administered. This may aid in the reproducibility of the results.
Limitations
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration. As such, results should be interpreted with caution and in the context of the overall clinical picture.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 12437-0
- 73932-6
- 73973-0
- 31208-2
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
Red-top (no additive) tube or green-top (heparin) tube; gel-barrier tubes are not recommended
Collection Instructions
Transfer separated serum to a plastic transport tube. Trough levels are most reproducible.
Storage Instructions
Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.
