Uric Acid, 24-Hour Urine
Use
Look for hyperuricosuria in patients with renal calculus formation. Identification of overexcretors re: risks of stone formation, identification of genetic defects, influence of overexcretion on therapy of gout. Uric acid nephrolithiasis occurs in primary gout or in secondary hyperuricemia (eg, malignant diseases). Uric acid nephrolithiasis may complicate ulcerative colitis, Crohn's disease, and surgical jejunoileal bypass. Most subjects with uric acid stones do not have gout.1 Evaluate uric acid metabolism in gout.
Special Instructions
State urine volume on the request form. Ensure the specimen is well mixed before sending for analysis.
Limitations
Even mild renal failure can reduce uric acid excretion, potentially affecting test results. Similarly, conditions like hypertension can decrease uric acid excretion, which should be considered when interpreting results. Proper labeling is critical as improper labeling can lead to specimen rejection, as can the use of preservatives or a pH level below 6.
Methodology
Other
Biomarkers
LOINC Codes
- 3087-4
- 3086-6
- 3087-4
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
10 mL aliquot of entire collection
Minimum Volume
1 mL aliquot
Container
Plastic urine container, no preservative
Collection Instructions
Mix well.
Patient Preparation
Standard diet 24 hours prior to collection
Storage Instructions
Maintain specimen at room temperature or refrigerate.
Causes for Rejection
Improper labeling; use of preservative; pH <6
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |