Special Instructions

A hereditary cancer clinical questionnaire should be submitted with all specimens. Contact CMBP genetic services at 800-345-4363 to coordinate testing. To order Oragene Dx 500 saliva collection kits using PeopleSoft No. 87917, contact your local Labcorp branch supply department.

Limitations

Sequencing cannot detect variants not covered by this analysis, including noncoding or deep intronic variants, and may not reliably detect changes in repetitive elements like microsatellite repeats. It may not detect mosaic variants, inversions, or other genomic rearrangements such as transposable element insertions. Sequence analysis may also be affected by allele drop-out due to a rare variant under a primer site or homopolymeric regions. This assay may not detect certain genomic rearrangements such as translocations, inversions, or some partial exon rearrangements. The presence of pseudogenes can interfere with variant detection in genes like PMS2. This test is not intended to detect somatic variants. Bone marrow transplantation may affect results.

Biomarkers

LOINC Codes

Result Turnaround Time

Related Documents

Stability Requirements