6-Monoacetylmorphine Confirmation, Random, Urine
Use
Determination of heroin use. 6-Monoacetylmorphine (6-MAM) is a unique metabolite of heroin, and its presence is a definitive indication of recent heroin use. While heroin is rapidly metabolized and rarely found in urine, 6-MAM provides conclusive evidence of heroin consumption. As heroin has a short detection window, this test is crucial for confirming recent use.
Special Instructions
For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. No specimen substitutions are accepted. Chain-of-custody testing should be ordered under 6MAMX. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine. Additional drug panels are available on request by calling 800-533-1710 or 507-266-5700. STAT requests are not accepted for this test.
Limitations
The absence of 6-MAM does not rule out heroin use due to its short half-life and rapid metabolism. 6-MAM is typically only detectable within 24 hours of heroin use. Morphine will typically be detectable 1 to 2 days after 6-MAM is no longer measurable. The presence of morphine alone is insufficient to prove heroin use.
New York Approved
Methodology
Mass Spectrometry (GC-MS)
Biomarkers
LOINC Codes
- 19593-3
- 19593-3
- 69050-3
- 77202-0
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
10 mL
Minimum Volume
2.1 mL
Container
Plastic, 10-mL urine tube
Collection Instructions
Collect a random urine specimen. No preservative.
Causes for Rejection
No gross hemolysis or icterus acceptance limitations specified.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 14 days |
| Frozen | 14 days |