Alpha-Amylase, IgE, Serum

Casandra

Casandra Test Code MC89359Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID AAMYCPT Code 86008

Alpha-Amylase, IgE, Serum

Clinical Use

Use

The Alpha-Amylase, IgE test is useful for establishing the diagnosis of an allergy to Alpha-Amylase and defining the specific allergen responsible for eliciting allergic signs and symptoms. It helps in identifying allergens responsible for allergic responses and/or anaphylactic episodes, and can confirm sensitization prior to the beginning of immunotherapy. The test is crucial in investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. It is important to note that testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients for whom the medical management does not depend upon identification of allergen specificity.

Special Instructions

For a listing of allergens available for testing, see the allergens IgE antibodies PDF provided by Mayo Clinic Laboratories. If not ordering electronically, complete, print, and send an Allergen Test Request form (T236) with the specimen.

Limitations

The test is not useful for patients who have undergone immunotherapy or for those where the management does not rely on specific allergen identification. Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies, leading to potential false positives. Moreover, individuals with markedly elevated serum IgE (>2500 kU/L) may exhibit false-positive results due to nonspecific binding. Hence, test results must be interpreted in the clinical context.

Test Details

FDA Approved