Alpha/Beta Crystallin IHC, Technical Component Only
Use
The test is useful for characterization of neuroectodermal tumors by identifying the presence of alpha-beta crystallin, a lens protein and a member of the superfamily of small heat shock proteins. This protein is expressed in various tissues and inclusion bodies, which can be indicative of certain disease states.
Special Instructions
This test includes only the technical performance of the stain without pathologist interpretation. It should not be ordered with PATHC, and if ordered together, the technical component will be canceled. Digital images are available only for electronic orders.
Limitations
The performance of the test is limited by the age of the paraffin section, which can affect immunoreactivity. Environmental factors may alter the charge of glass slides, affecting staining results. The stability of slide sections varies widely, and precautions should be taken to limit exposure to humidity, heat, and prolonged storage.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Attach the green pathology address label and the pink Immunostain Technical Only label to the transport container.
Storage Instructions
Store ambient or refrigerated.
Causes for Rejection
Wet/frozen tissue, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, snowcoat slides.