Alpha-Fetoprotein (AFP) Immunostain, Technical Component Only
Use
Alpha-fetoprotein (AFP) is an oncofetal antigen normally expressed in fetal liver, but not present in normal adult tissues. It can be expressed in yolk sac tumors and in hepatocellular carcinomas. This test aids in the identification of yolk sac tumors and hepatocellular carcinoma.
Special Instructions
Not provided.
Limitations
This test does not include pathologist interpretation, only technical performance of the stain. The charge of glass slides can be affected by environmental factors and may alter slide staining. Age of a cut paraffin section can affect immunoreactivity. Stability thresholds vary among antigens.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Alpha-Fetoprotein
Protein
LOINC Codes
- Order only; no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Attach the green pathology address label and the pink Immunostain Technical Only label included in the kit to the outside of the transport container.
Causes for Rejection
Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides, Snowcoat slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient preferred |