Alpha Follicle Stimulating Hormone Immunostain, Technical Component Only
Use
This test may aid in the classification of pituitary adenomas by detecting alpha subunit of follicle stimulating hormone (FSH) which is a component common to all glycoprotein hormones produced by the anterior pituitary. Glycoprotein hormone-producing cells constitute approximately 30% of the total cell population in normal pituitary and stain in a cytoplasmic pattern. Immunohistochemical detection of alpha-FSH is useful in identifying these cells, which can contribute to better understanding and classification of pituitary adenomas.
Special Instructions
Not provided.
Limitations
This test does not include pathologist interpretation, only technical performance of the stain. Pathologist interpretation should be performed in the context of the patient’s clinical history and other diagnostic tests. The age of a cut paraffin section can affect immunoreactivity; paraffin sections should be cut within 6 weeks. The charge of glass slides can be influenced by environmental factors and may alter slide staining. Sending unsuitable glass slides can result in inconsistent staining.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Alpha FSH
Protein
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Causes for Rejection
Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides, Snowcoat slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |