Amoxicillin, IgE, Serum
Use
The test aids in establishing a diagnosis of an allergy to amoxicillin by identifying IgE antibodies specific to the allergen. It is also used for defining the allergen responsible for allergic symptoms, identifying allergens responsible for allergic responses or anaphylactic episodes, confirming sensitization before starting immunotherapy, and investigating specificity of allergic reactions to insect venom, drugs, or chemical allergens. Testing for IgE antibodies is not considered useful for patients previously treated with immunotherapy or when allergen identification does not influence clinical management.
Special Instructions
For a listing of available allergens for testing, refer to the Allergens - Immunoglobulin E (IgE) Antibodies PDF. If not ordering electronically, complete and submit the Allergen Test Request form (T236) along with the specimen.
Limitations
False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE levels (>2500 kU/L) due to nonspecific binding to allergen solid phases. Some individuals with clinically insignificant sensitivity to allergens may still have measurable IgE antibody levels; thus, results must be interpreted in clinical context. This test is not useful for assessing residual clinical sensitivity in patients treated with immunotherapy when medical management does not depend on allergen specificity.
FDA ApprovedNew York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 6829-6
- 6829-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen; (0.05 mL x number of allergens) + 0.25 mL deadspace for more than 1 allergen
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK; Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |