Anti-optic nerve autoantibodies, WB
Use
The detection of anti-optic nerve autoantibodies in the serum is significant for diagnosing autoimmune optic neuropathies and related disorders. These antibodies are typically present in patients with autoimmune conditions affecting the optic nerve. The results of this test aid in confirming the diagnosis and managing patients' treatment plans effectively by providing insights into the underlying autoimmune processes.
Special Instructions
Complete and submit with the specimen a completed OHSU Ocular request form, clinical history, and referring physician information (name & phone number). Note: Without this information, testing cannot be completed.
Limitations
While highly specific, the presence of anti-optic nerve autoantibodies might not be detectable in all patients with optic neuritis, particularly if the disease is not autoimmune in nature. Additionally, false positives may occur in certain conditions, and the interpretation of results should always be done in conjunction with clinical findings. Comprehensive clinical assessment and correlation with other diagnostic tests are recommended for an accurate diagnosis.
New York Approved
Methodology
Immunoassay (Western Blot)
Biomarkers
Result Turnaround Time
16-35 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
5 mL
Minimum Volume
3 mL
Container
plastic vial
Collection Instructions
Draw blood in a plain, red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 5 mL serum refrigerated in a plastic vial.
Causes for Rejection
Hemolysis: Mild reject; Gross reject. Thawing: Warm reject; Cold OK.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |