Anti-SAE1 Ab, IgG

Casandra

Casandra Test Code MC36675Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID FAS1ACPT Code 83516

Clinical Use

Use

Anti-SAE1 antibodies, IgG type, are evaluated for their clinical significance in autoimmune responses associated with dermatomyositis. Detection of these antibodies can aid in diagnosing patients with specific autoimmune myopathies, contributing to better patient management and therapy planning. The presence of these antibodies is often correlated with specific clinical characteristics, including skin manifestations and muscle weakness, commonly seen in dermatomyositis.

Special Instructions

For accurate results, ensure proper sample collection and timely transportation under the specified conditions. Follow collection instructions carefully, especially regarding centrifugation and aliquoting. Coordination with the testing laboratory may be necessary to align with specimen stability requirements. Be aware of potential interferences related to hemolysis, lipemia, and icterus, which may result in sample rejection.

Limitations

This test is not FDA approved and should be interpreted within the broader clinical context, taking into account the patient's full clinical profile and other laboratory findings. Only samples meeting the specified volume and stability conditions yield reliable results. Hemolysis, lipemia, or icterus could interfere with the accuracy of the test, leading to possible false-negative or false-positive results. Repeat testing may not be feasible with minimum volume samples due to limited material.

Test Details

New York Approved