Antibody Screen with Reflexed Antibody Identification, Blood
Use
Detection of allo- or autoantibodies directed against red blood cell antigens in the settings of pretransfusion testing. This test is also useful for evaluating transfusion reactions and hemolytic anemia. It identifies irregular red cell alloantibodies, which are present in 2% to 4% of the general population and may cause hemolytic disease of the newborn or hemolysis of transfused donor red blood cells.
Special Instructions
Not provided.
Limitations
Clinical evaluation of antibodies identified is necessary to determine their potential harm and to assess appropriate action. Hemagglutination method is used, which involves the use of three type O erythrocytes with known expression of common antigenic determinants. Specimen handling errors, such as gross hemolysis, can lead to rejection.
FDA Approved
Methodology
Other
Biomarkers
Unknown antibody
Antibody
LOINC Codes
- 101678-1 - Bld gp Ab Scn Bld NB Ql
- 890-4 - Bld gp Ab Scn SerPl Ql
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
6 mL
Minimum Volume
3 mL
Container
Pink top (EDTA)
Collection Instructions
Send whole blood specimen in original tube. Do not aliquot.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 days |
| Refrigerated | 4 days |