Antidepressant Drug Screen, Ur, Quantitative
Use
This test is used for the quantitative analysis of antidepressants in urine, providing a precise measurement of drug concentration. It helps in the identification and quantification of various antidepressant compounds such as amitriptyline, clomipramine, desipramine, doxepin, fluoxetine, imipramine, maprotiline, nortriptyline, paroxetine, protriptyline, sertraline, and trimipramine. The test is crucial for monitoring therapeutic levels, identifying potential overdose, and assessing patient compliance with medication regimens.
Special Instructions
Not provided.
Limitations
The quantitative analysis may be affected by sample contamination or improper preservation methods. Interfering substances in urine could lead to false positives or negatives, and results should be corroborated with clinical findings. Detection is limited to the specific antidepressants listed and does not account for additional psychoactive substances that are not part of this panel.
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 32136-4 - Antidepressants Ur Ql
- 32136-4 - Antidepressants Ur Ql
- 16225-5 - Amitrip Ur Ql Cfm
- 61427-1 - Nortrip Ur Ql Cfm
- 61418-0 - Imipramine Ur Ql Cfm
- 61412-3 - Desipramine Ur Ql Cfm
- 32112-5 - Sertraline Ur Ql
- 75233-7 - Norsertraline Ur Ql
- 19471-2 - FLUoxetine Ur Ql Cfm
- 19629-5 - Norfluoxetine Ur Ql Cfm
- 45144-3 - clomiPRAMINE Ur Ql
- 58013-4 - Norclomipramine Ur Ql
- 61415-6 - Doxepin Ur Ql Cfm
- 58014-2 - Nordoxepin Ur Ql
- 3737-4 - Maprotiline Ur Ql
- 4001-4 - Protrip Ur Ql
- 4084-0 - Trimipramine Ur Ql
- 27109-8 - PARoxetine Ur Ql
- 14061-6 - Cyclobenzaprine Ur-mCnc
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
3 mL
Minimum Volume
0.6 mL
Container
Plastic container
Collection Instructions
Collect 3 mL random urine without preservatives. Ship refrigerated.
Storage Instructions
Ship refrigerated. Ambient storage is acceptable for 72 hours and frozen storage is stable for 30 days.
Causes for Rejection
NA for hemolysis, lipemia, and icterus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 14 days |
| Frozen | 30 days |
