Antidepressant Drug Screen, Ur, Quantitative
Use
This test is used for the quantitative analysis of antidepressants in urine, providing a precise measurement of drug concentration. It helps in the identification and quantification of various antidepressant compounds such as amitriptyline, clomipramine, desipramine, doxepin, fluoxetine, imipramine, maprotiline, nortriptyline, paroxetine, protriptyline, sertraline, and trimipramine. The test is crucial for monitoring therapeutic levels, identifying potential overdose, and assessing patient compliance with medication regimens.
Special Instructions
Specimens should be collected as 3 mL of random urine without preservatives and shipped refrigerated in a plastic container. Ensure proper labeling and avoid contamination to maintain sample integrity.
Limitations
The quantitative analysis may be affected by sample contamination or improper preservation methods. Interfering substances in urine could lead to false positives or negatives, and results should be corroborated with clinical findings. Detection is limited to the specific antidepressants listed and does not account for additional psychoactive substances that are not part of this panel.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 32136-4
- 32136-4
- 16225-5
- 61427-1
- 61418-0
- 61412-3
- 32112-5
- 75233-7
- 19471-2
- 19629-5
- 45144-3
- 58013-4
- 61415-6
- 58014-2
- 3737-4
- 4001-4
- 4084-0
- 27109-8
- 14061-6
Result Turnaround Time
3-9 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
3 mL
Minimum Volume
0.6 mL
Container
Plastic container
Collection Instructions
Collect 3 mL random urine without preservatives. Ship refrigerated.
Storage Instructions
Ship refrigerated. Ambient storage is acceptable for 72 hours and frozen storage is stable for 30 days.
Causes for Rejection
NA for hemolysis, lipemia, and icterus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 14 days |
| Frozen | 30 days |