Arsenic Occupational Exposure, Random, Urine
Use
Screening test for detection of occupational exposure to arsenic in random urine specimens. Provides a measure of recent arsenic exposure, with reflex speciation if total arsenic is ≥10 mcg/L to differentiate toxic inorganic/methylated forms from less harmful organic arsenic from dietary sources including seafood. It aids in interpreting exposure-related health risk but cannot predict health effects directly.
Special Instructions
Only orderable as part of a profile, paired with creatinine, with reflex to speciation if total arsenic ≥10 mcg/L. Metals Analysis Specimen Collection and Transport instructions should be followed, including avoidance of seafood for 48 hours prior to collection.
Limitations
Cannot predict whether arsenic levels will affect health. Consumption of seafood prior to collection may lead to misleadingly elevated total arsenic due to organic arsenic. Must interpret total arsenic in the context of speciation to determine true toxic exposure.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 13463-5
- 13463-5
- 5586-3
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
Specimen Volume: 6 mL (profile includes ASOU and creatinine)
Minimum Volume
3 mL
Container
Clean, plastic urine collection container; submission plastic vial or aliquot container with no metal cap or glued insert
Collection Instructions
Collect random urine specimen. Avoid seafood for 48 hours; avoid gadolinium- or iodine-containing contrast media for 96 hours prior to collection; recommended sampling at end of work week.
Patient Preparation
Avoid seafood for 48 hours, wait 96 hours after gadolinium or iodine contrast media administration.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient: 72 hours |
| Refrigerated | Refrigerated: 28 days |
| Frozen | Frozen: 28 days |