Bartonella Antibody Panel, IgG and IgM, Serum
Use
This test is useful for the diagnosis of Bartonella infection, especially in the context of a cat scratch. Bartonella henselae and Bartonella quintana are small, rod-shaped, pleomorphic, gram-negative bacteria. The human body louse is the proposed vector for B. quintana, with no animal reservoir determined. The domestic cat is believed to be both a reservoir and vector for B. henselae. Cats may infect humans directly through scratches, bites, or licks, or indirectly through an arthropod vector. Bartonella lesions typically appear as aggregates that proliferate rapidly, with significant disease symptoms in humans.
Special Instructions
Not provided.
Limitations
Normal serum IgG titers are usually less than 1:128, but 5% to 10% of healthy controls can show a titer of 1:128. IgM titers in normal serum are typically less than 1:20. This test was developed by Mayo Clinic in a manner consistent with CLIA requirements, but it has not been cleared or approved by the FDA.
New York Approved
Methodology
Immunoassay (Immunofluorescence Assay)
Biomarkers
Bartonella henselae
MicroorganismBartonella quintana
Microorganism
LOINC Codes
- 90251-0 - B henselae+quintana IgG+IgM Pnl Titr Ser
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.15 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into plastic vial.
Causes for Rejection
Gross hemolysis, Gross lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 30 days |
| Frozen | 30 days |