Benzene as Phenol, Occupational Exposure, Urine
Use
This test is used for monitoring occupational exposure to benzene by measuring its metabolite, phenol, in urine. Benzene is an industrial chemical that can pose significant health risks; thus, monitoring of exposure helps in preventive health efforts for workers in industries such as chemical manufacturing, oil refining, and shoe manufacturing. Phenol, an intermediate in benzene metabolism, serves as a biomarker to evaluate exposure levels and potential risks to health from benzene.
Special Instructions
For accurate results, collect a random urine sample without preservatives and ship it refrigerated in a plastic container to maintain sample integrity. This test is available in New York State, facilitating its use by clients in that region.
Limitations
The test specifically measures phenol as a marker of benzene exposure, but it cannot distinguish between exposure from industrial sources and other possible environmental or dietary sources of phenol. Additionally, individual metabolic differences can affect phenol levels, so results should be interpreted considering the broader context of occupational exposure history.
Methodology
Mass Spectrometry (Gas Chromatography/Flame Ionization Detection (GC-FID))
Biomarkers
LOINC Codes
- 2161-8
- 2758-1
- 13487-4
Result Turnaround Time
7-11 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
10 mL
Minimum Volume
1.2 mL
Container
plastic container
Collection Instructions
Collect a random urine sample without preservatives and ship refrigerated.
Causes for Rejection
NA
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 180 days |
