Benzodiazepines Confirmation, Random, Urine
Use
This test is useful for detecting drug use involving benzodiazepines such as alprazolam, chlordiazepoxide, clonazepam, diazepam, and other related compounds. Benzodiazepines are drugs frequently prescribed in western countries due to their efficacy, safety, minimal side effects, and demand for sedative agents. This test can detect parent drugs and their metabolites to support clinical assessments of benzodiazepine use or abuse.
Special Instructions
Not provided.
Limitations
This test may not detect all metabolites of benzodiazepines if sample integrity is compromised, such as through hemolysis or icterus. Moreover, STAT requests are not accepted, potentially affecting clinical turnaround time for urgent assessments. The extensive metabolism of benzodiazepines might result in the non-detection of the parent compound, presenting challenges in interpretation of low concentrations.
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 90890-5 - Benzodiazepines Pnl Ur Cfm
- 59615-5 - Alpraz Ur Cfm-mCnc
- 16348-5 - A-OH Alpraz Ur Cfm-mCnc
- 20522-9 - Chlordiazep Ur Cfm-mCnc
- 16229-7 - clonazePAM Ur Cfm-mCnc
- 51776-3 - 7Aminoclonazepam Ur Cfm-mCnc
- 16227-1 - diazePAM Ur Cfm-mCnc
- 16228-9 - Nordiazepam Ur Cfm-mCnc
- 16233-9 - Midazolam Ur Cfm-mCnc
- 59590-0 - 1OH-midazolam Ur Cfm-mCnc
- 16201-6 - Oxazepam Ur Cfm-mCnc
- 20559-1 - Temazepam Ur Cfm-mCnc
- 59635-3 - cloBAZam Ur Cfm-mCnc
- 97160-6 - Norclobazam Ur Cfm-mCnc
- 20528-6 - Flunitrazepam Ur Cfm-mCnc
- 51777-1 - 7Aminoflunitrazepam Ur Cfm-mCnc
- 16231-3 - Flurazepam Ur Cfm-mCnc
- 97159-8 - 2-OH-Ethylfluraz Ur Cfm-mCnc
- 17088-6 - LORazepam Ur Cfm-mCnc
- 17479-7 - Prazepam Ur Cfm-mCnc
- 16232-1 - Triazolam Ur Cfm-mCnc
- 49876-6 - A-OH-triazolam Ur Cfm-mCnc
- 72770-1 - Zolpidem Ur Cfm-mCnc
- 72768-5 - Zolpidem phenyl-4-carb Ur Cfm-mCnc
- 69050-3 - Toxicologist review
Result Turnaround Time
2-6 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
1 mL
Minimum Volume
1 mL
Container
Plastic, 5-mL tube
Collection Instructions
1. Collect a random urine specimen. 2. No preservative.
Causes for Rejection
Gross hemolysis, Icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 14 days |
