BRAF V600E Immunostain, Technical Component Only
Use
This test is useful for the identification of BRAF V600E-mutated protein, which is important for various clinical disorders such as melanoma, colorectal cancer, papillary thyroid carcinoma, hairy cell leukemia, and more. The BRAF V600E alteration leads to constitutive activation of the mitogen-activated protein kinase pathway, which plays a crucial role in cell proliferation and tumorigenesis.
Special Instructions
Not provided.
Limitations
The test does not include pathologist interpretation; it is solely limited to the technical performance of the stain. Possible issues could arise due to conditions such as age of paraffin sections, improper slide handling, and environmental factors affecting glass slide chemistry. Appropriateness for specific antigens may vary with storage and exposure to heat or humidity.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
No genes
Gene
LOINC Codes
- Order only;no result
- Bill only; no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Causes for Rejection
Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides, Snowcoat slides