Buprenorphine and Norbuprenorphine, Chain of Custody, Random, Urine
Use
The test is useful for monitoring compliance of buprenorphine therapy and detecting and confirming the illicit use of buprenorphine. Buprenorphine is commonly used as a substitution therapy for opioid dependence and as an analgesic. The test can detect the presence of buprenorphine and its metabolites in urine to determine if the patient has been using the drug as prescribed or illicitly. The chain of custody process is crucial when results could be used in legal contexts, ensuring that the specimen is always under control of authorized personnel to prevent tampering.
Special Instructions
This test requires a chain-of-custody process, making it suitable for scenarios where results could influence legal outcomes. It includes the Chain of Custody Kit (T282) containing necessary containers, seals, and documentation. Proper collection and sealing of specimens as per provided instructions are essential.
Limitations
The test results reflect urine concentrations of buprenorphine and its metabolites but do not correlate well with serum drug levels. They are not intended for therapeutic drug management. The enzyme immunoassay is a preliminary screen, and results above the cutoff concentration should be confirmed by more specific methods like LC-MS/MS. Potential interfering substances or improper specimen handling may affect test outcomes.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 69033-9
- 58359-1
- 3415-7
- 49753-7
- 77202-0
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL
Minimum Volume
1 mL
Container
Chain of custody kit containing specimen containers, seals, and required documentation.
Collection Instructions
Collect specimen in the container provided, seal, and submit with the associated documentation to satisfy the legal requirements for chain-of-custody testing.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |