Cadmium for Occupational Monitoring, Blood
Use
This test is useful for detecting exposure to cadmium, a toxic heavy metal, as part of occupational monitoring. Cadmium toxicity resembles that of other heavy metals like arsenic, mercury, and lead, primarily affecting the kidneys and leading to kidney dysfunction with proteinuria over time. Chronic exposure is often from occupational sources such as spray painting with organic-based paints or exposure to tobacco smoke.
Special Instructions
It is important to note that high concentrations of gadolinium and iodine may interfere with mass spectrometry-based metal tests. Therefore, blood samples should not be collected within 96 hours of administration of gadolinium- or iodine-containing contrast media.
Limitations
The test may not detect acute cadmium exposure as elevated blood levels may be transient. The primary limitation is the potential interference from other metal exposures or contaminants not accounted for during the sampling process, which may affect the specificity of the results.
New York Approved
Methodology
Mass Spectrometry (ICPS MS)
Biomarkers
LOINC Codes
- 5609-3
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
1 mL
Minimum Volume
0.25 mL
Container
Royal blue-top BD vacutainer with EDTA blood collection tube
Collection Instructions
Send whole blood specimen in original collection tube. Do not aliquot. See Metals Analysis Specimen Collection and Transport for complete instructions.
Patient Preparation
Specimen should not be collected for 96 hours after administration of gadolinium- or iodine-containing contrast media.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 28 days |
| Refrigerated | 28 days |
| Frozen | 28 days |