Carbamazepine, Total, Serum
Use
Carbamazepine is used for monitoring therapy, determining compliance, and assessing toxicity in patients. It is crucial for managing partial seizures with temporal lobe and psychomotor symptoms, as well as generalized tonic-clonic seizures. Additionally, it aids in providing analgesia in trigeminal neuralgia.
Special Instructions
Not provided.
Limitations
Carbamazepine-10,11-epoxide (CBZ10-11) is not reported by this test. Toxicity associated with carbamazepine overdose occurs when blood levels are 15.0 mcg/mL or higher, leading to severe symptoms such as irregular breathing and impaired consciousness. Always document baseline hematologic data before treatment initiation due to potential side effects like aplastic anemia and agranulocytosis.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Other)
Biomarkers
Carbamazepine
Analyte
LOINC Codes
- 3432-2 - carBAMazepine SerPl-mCnc
- 3432-2 - carBAMazepine SerPl-mCnc
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.25 mL
Container
Red top, Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 7 days |
| Frozen | 28 days |